Leukocyte-Activating Peptides for Immunotherapy
This invention provides immunocyte-stimulating peptides and synthetic methods for the peptides. The peptide induces an immune response by playing a key role in the movement of target cell, secretion of arachiodonic acid, the generation of superoxides, or the activating of phospholiphase. The peptide can be used for immune-related disease.
Benefits and Applications
Peptides activating immunocyte are identified, and the efficient synthetic method of the same.
Providing a peptide that selectively activates phospholipase A2 closely invovled in inflammation, immune response and differentiation of immunocyte.
Providing a peptide that induces immune reaction by specifically binding to a chemoattractant receptor such as FPR and FPRL1.
Potential applications: Immunomodulator and adjuvants, antibaterial and antiviral agent, supplemental agent for anticancer drug
Intellectual Property Status
Patent pending (PCT)
Biochem Pharmacol. 2003 Nov 1; 66(9): 1841-51.
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