Recombinant Mussel Adhesive Protein for Medical and Industrial Application

Description
This technology provides a protein expression system expressing highly value added proteins such as a mussel protein in E.coli by genetic technology. This technology allows to produce the mussel adhesive protein at high yield and to improve a separation and purification process, resulting in large scale production and purification of mussel adhesive suitable for medical use. The recombinant protein demonstrated significant adhesive properties for potential use in aqueous and medical environments.
Benefits and Applications
Novel and chimeric genes that produce mussel adhesive protein were identified
Providing mussel adhesive protein with excellent adhesive strength
Providing a protein expression system in E.coli which can increase the yield of the adhesive protein
Efficient separation and purification of high purity mussel protein is developed
Large scale production system of adhesive protein is under development
Intellectual Property Status
Patent pending (PCT, US)
Related Publication
Biotechnology and Applied Biochemistry. 2003, 37(2): 103-107
Enzyme and Microbial Technology. 2003, 33(4), 460-465
Applied and Environmental Microbiology. 2004, 3352-3359
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