Description

This technology provides a protein expression system expressing highly value added proteins such as a mussel protein in E.coli by genetic technology. This technology allows to produce the mussel adhesive protein at high yield and to improve a separation and purification process, resulting in large scale production and purification of mussel adhesive suitable for medical use. The recombinant protein demonstrated significant adhesive properties for potential use in aqueous and medical environments.

Benefits and Applications

Novel and chimeric genes that produce mussel adhesive protein were identified

Providing mussel adhesive protein with excellent adhesive strength

Providing a protein expression system in E.coli which can increase the yield of the adhesive protein

Efficient separation and purification of high purity mussel protein is developed

Large scale production system of adhesive protein is under development

Intellectual Property Status

Patent pending (PCT, US)

Related Publication

Biotechnology and Applied Biochemistry. 2003, 37(2): 103-107

Enzyme and Microbial Technology. 2003, 33(4), 460-465

Applied and Environmental Microbiology. 2004, 3352-3359

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